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Original Article

Long-pulse Nd:YAG 1064-nm laser treatment for onychomycosis

Published Online: 20 September 2012

Abstract

Abstract: Background Recent research shows that lasers can inhibit fungal growth and that Nd:YAG 1064-nm lasers can penetrate as deep as the lower nail plate.The aim of this study was to observe the effect of a long-pulse Nd:YAG 1064-nm laser on 154 nails of 33 patients with clinically and mycologically proven onychomycosis.Methods Thirty-three patients with 154 nails affected by onychomycosis were randomly assigned to two groups,with the 154 nails divided into three sub-groups (Ⅱ degree,Ⅲ degree,and Ⅳ degree) according to the Scoring Clinical Index of Onychomycosis.The 15 patients (78 nails) in group 1 were given eight sessions with a one-week interval,and the 18patients (76 nails) in group 2 were given four sessions with a one-week interval.Results In group 1,the effective rates at 8 weeks,16 weeks,and 24 weeks were 63%,62%,and 51%,respectively,and the effective rates in group 2 were 68%,67%,and 53% respectively.The treatment effect was not significantly different between any sub-group pair (P >0.05).Conclusions Long pulse Nd:YAG 1064-nm laser was effective for onychomycosis.It is a simple and effective method without significant complications or side effects and is expected to become an alternative or replacement therapy for onychomycosis.

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Published In

Go to Chinese Medical Journal homepage
Chinese Medical Journal
Volume 125Number 1820 September 2012
Pages: 3288 - 3291

History

Published online: 4 September 2021

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Keywords

  1. onychomycosis
  2. laser
  3. treatment

Authors

Affiliations

ZHANG Rui-na
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
WANG Dong-kun
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
ZHUO Feng-lin
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
DUAN Xiao-han
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China
ZHANG Xiao-yan
Department of Dermatology, China-Japan Friendship Hospital,Beijing 100029, China
ZHAO Jun-ying
Department of Dermatology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

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